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The ago-allosteric small molecule compound 2 enhances binding of the agonist GLP-1 but does not affect binding of the antagonist exendin (9-39) and it cannot be inhibited by the peptide antagonist exendin (9-39), which is not surprising considering the intracellular binding site of compound 2 32,35,36

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May your provider choices stay informed, your medications stay potent, and your results stay lasting.

If you choose to drink on semaglutide , do so in moderation and be aware that your tolerance may be lower than usual

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