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Mn uptake via voltage-gated calcium channels in dopaminergic neurons has also been reported (Dui et al., 2013), but again at high Mn concentrations

A recent study demonstrated that neuroinflammation could evoke depressive symptoms such as anhedonia and motor retardation (Felger and Treadway, 2017)

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Grossly, may be solid or soft, single or multiple, and of various colors including white and pigmented (yellow, grey)