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doi: 10.1038/sj.ijir.3901139 111 DiamondLEEarleDCHeimanJRRosenRCPerelmanMAHarningR

When the heart lacks ATP, it struggles to maintain the strong, coordinated contractions required to sustain blood pressure upon standing

It was believed previously that the number of adipocytes could increase substantially only during the infancy and childhood and that an excess of energy in children leads to "hyperplastic" obesity associated with increased number of adipocytes

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Common side effects include nausea, vomiting, and diarrhoea, typically transient and diminishing over 48 weeks with gradual dose escalation

Wada T, Anker SD, Liu Z, et al