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Although GLP-1 drugs are generally considered safe to use, its recommended to avoid them if you have or had: Personal or family history of thyroid cancer Family history of multiple endocrine neoplasia 2 (MEN-2) Pancreatitis Used other anti-obesity medications These medications can aggravate the above conditions, which may lead to serious health complications

Xu X, Li Y, Wu Y, Wang M, Lu Y, Fang Z, et al

Holmes et al., 1999

Baseline characteristics of the patient population in the Saxagliptin Assessment of Vascular Outcomes Recorded in patients with diabetes mellitus (SAVOR)-TIMI 53 trial

GLP-1 receptor agonists have demonstrated anti-inflammatory effects in both animal and human studies

Despite limitations of comparisons across trials, some overall themes emerge