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4.3 Contraindications Hypersensitivity to Vitamin B1, B6 and/or B12 or any of the excipients of NEUROBION AMPOULES (see section 6.1)

5-Amino-1-methylquinolinium (5-Amino-1MQ) is a small-molecule inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT) an enzyme linked to metabolic rate regulation, fat storage, and cellular energy balance

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The kidney and cardiovascular effects of current and next-generation incretin and metabolic hormone therapies remain an area of active investigation