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Previous reports have shown that relatively high levels of mTOR complex 1 (mTORC1) signaling prevail in MZB 36,37 , but that the maturation of FoB downregulates the mTORC1/Akt pathway 38

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Shealy DJ, Cai A, Staquet K, et al

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Proc Natl Acad Sci USA 94:75317536 Huot P, Johnston TH, Fox SH, Newman-Tancredi A, Brotchie JM (2015) The highly-selective 5-HT(1A) agonist F15599 reduces L-DOPA-induced dyskinesia without compromising anti-parkinsonian benefits in the MPTP-lesioned macaque