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Here's a quick comparison: While dosing schedules appear similar, retatrutide's triple-receptor mechanism (GLP-1 + GIP + glucagon) produces different effects than dual-agonists like tirzepatide or single-agonists like semaglutide

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Does the diarrhea get worse at higher retatrutide doses

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Retatrutide works by mimicking the actions of three important hormones: GLP-1, GIP and GCG

Researchers comparing compounds pre-purchase can review our retatrutide vs semaglutide vs tirzepatide breakdown