The primary allosteric activators of GDH are ADP and leucine
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Symptoms were generally mild and effectively managed with supportive care, including the use of antiemetics administered according to clinical need
Each of these is involved in how the body manages energy, responds to insulin (the hormone that controls blood sugar), and processes fat
Further research is warranted to elucidate the full therapeutic potential of GLP-1 RAs in AS but like many genetic kidney diseases, Alport syndrome patients have been excluded from important clinical trials exploring therapeutics that slow the progression of CKD
