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Symptoms may include: Shortness of breath Red, flushed skin Headaches Rapid weight gain, polycythemia (increased red cell mass), hypokalemia, CHF, pulmonary edema, and vascular thrombosis are mostly observed in therapeutic contexts where vitamin B12 is administered aggressively or over extended periods

In the body, they often serve as an inter-cellular communication system

They outperformed untreated middle-aged mice