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FOXO4-DRI is studied in preclinical longevity models to evaluate how senescent cell clearance influences biological aging markers

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Transcriptome analysis identified 4530 differentially expressed genes, with upregulation of those involved in glutathione metabolism, glycolysis (Embden-Meyerhof-Parnas pathway), the tricarboxylic acid cycle, oxidative phosphorylation, and the mitogen-activated protein kinase (MAPK) signaling pathway

A balanced gut can help keep things moving