Duloxetine significantly reduces pain scores and improves functional outcomes
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While B12 is naturally found in foods like meat, eggs, and dairy, some individuals have difficulty absorbing enough through diet alone
this effect is usually dose-related with an onset that varies widely from 1 to 2 months to over a year
The review found only four trials comparing CHCs with placebo, of which only one followed patients for over a year (238), whilst the remaining three followed weight changes over only 6-9 cycles
