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Weekly dosing allows tirzepatide to gradually accumulate until stable levels are reached

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P.et al (2009)

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eating a balanced diet and taking regular exercise remains essential for getting the most out of your treatment

Additional contributing factors include: Prolonged gastric distension due to delayed emptying Changes in gastric motility patterns Individual anatomical variations, such as hiatus hernia Concurrent use of other medications that affect gastric function It is worth noting that obesity itself is a significant risk factor for GORD, as excess abdominal adiposity increases intra-abdominal pressure