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Subsequent studies have shown that this phenomenon could be linked to a slowing of gastric emptying by GLP-1, as well as by the action of this hormone at the level of certain neural circuits of the brain involved in the suppression of appetite and the development of nausea
In some cases, patients may experience feelings of sadness, anxiety, or a general flatness of mood
Other first-generation GLP-1 medications include liraglutide, a synthetic form of the peptide with fatty acids attached for increased stability
A 2023 study found on a lower dose of GLP-1, participants lost on average 4.8% of lean body mass in just 24 weeks (Jiang et al, 2023)
Semaglutide is an FDA-approved medication originally developed for type 2 diabetes, but it has also gained recognition for its effectiveness in supporting weight loss