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Indeed, T2D and obesity/overeating as well as HF are recognized conditions of relative resistance to diuretics, and empagliflozin in subjects with T2D and chronic, stable HF has been demonstrated to be synergistic with bumetanide in increasing the fractional excretion of sodium also after 14 days of treatment [95] without affecting RAAS tone

For example, scales to evaluate the MedDiet used in the studies we reviewed range from 8- to 24-point scores, thus emphasizing different dietary components (Table 1)

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consult your doctor if any adverse reactions occur

JDC, MEL, JCH, and AS wrote the manuscript

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