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(2) prospective observational studies conducted with participants at least 18 years of age

There are other imaging modalities which are not routinely used, such as upper GI Barium studies and Single-Photon Emission Computed Tomography (SPECT)

Diligently follow your treatment for whatever is causing the hyperpigmentation as your dermatologist prescribes

Very few providers are willing to put their money where their mouth is like that