Although a lot of the evidence is based on cell models they did find that p-IGF-1R/IR positivity in ER+ breast cancer is associated with reduced benefit from adjuvant tamoxifen in postmenopausal patients
BMC Gastroenterol 21:10 Teng MS, Yeh KH, Hsu LA, Chou HH, Er LK, Wu S et al (2023) Differential effects of ABCG5/G8 gene region variants on lipid profile, blood pressure status, and gallstone disease history in Taiwan
Realistic expectations include progressive weight loss over a 12-20 week initial period, with the most significant changes becoming apparent after dose escalation is complete
(PubMed) Alvarez-Sabin J, Ortega G, Jacas C, et al
Smoking can modulate immune function and increase the production of thyroid-stimulating immunoglobulins, exacerbating the autoimmune process
76 WangC.KavalaliE.MonteggiaL