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Known and theoretical safety concerns include: Retatrutide (and the GLP-1 receptor agonist class): Nausea, vomiting, diarrhoea, and reduced appetite are the most commonly reported side effects

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One study showed, for example, that fibroblasts from ARDS patients are more prone to ferroptosis than normal fibroblasts themselves (58)

Expect the strongest early appetite change and the highest chance of nausea

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It is also explored by patients who suffer from gastrointestinal problems such as inflammatory bowel disease (IBD), ulcers, or leaky gut syndrome, as it may help repair the gut lining and reduce inflammation in the digestive system