glp-1 anhedonia Doctors and patients across social media are reporting a kind of emotional flattening while on drugs. Anecdotally, physicians describe meaningful mental health gains — greater self-esteem, less shame over eating and GLP-1s are fantastic for weight-loss

The insulin/IGF-1 signaling pathway seems to be an evolutionarily well-conserved mechanism involved in the regulation of longevity in species ranging from metazoans to mammals [1, 2]

doi: 10.1016/j.jep.2023.117464, 33

However, some Trulicity patients claim they have experienced concerning gastrointestinal problems, including bowel obstructions, pancreatitis, and gastroparesis

Glutathione is a naturally occurring molecule in the body and is generally very well-tolerated

As the central fat depots are metabolized, a relative redistribution of adipose tissue from visceral to subcutaneous regions may occur, at least under experimental conditions

You're already on GLP-1 to feel better