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I used to wake up tired, work tired, and go to bed tired like my body never fully charged

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Pharmacological inhibition of LONP1 reverses mitochondrial exhaustion in VHL-deficient tumors and restores sorafenib sensitivity in resistant cells, offering a precision strategy to overcome therapy resistance linked to VHL defects [167]

Moreover, iron is part of the prosthetic group of catalases, key antioxidant enzymes that counteract oxidative stress by catalyzing the reduction and detoxification of hydrogen peroxide

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