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This happens mostly in people with type 1 diabetes, but it can also occur in people with type 2 diabetes who have uncontrolled blood sugar

Figure 4.Cumulative Incidence Function: Time to First Occurrence of MACE in Study 1 Data from the in-trial period

Thus, by easing the impact obesity and type 2 diabetes have on the body, there is a positive "flow-on effect" to the kidneys

I aim for levels between 100 and 150 nmol/L

These human PK models projected that SEP-479 will have a human half-life in approximately the range of 43-87 hours following oral dosing

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