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Obtain a Detailed Letter of Medical Necessity Your providers letter must tie GLP1 medication to real, documented medical risks and interventions youve already tried

Clinical trials show approximately 2040% of total weight lost with GLP-1 medications includes lean mass, comparable to dietary restriction and bariatric surgery

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Twenty-four SpragueDawley rats were randomly divided into four groups: control, REB (100 mg/kg orally for 10 days), LPS (5 mg/kg intraperitoneally on day 10), and REB + LPS (REB pretreatment for 10 days followed by LPS injection on day 10)

Experiment with different times to find what works best for your body and schedule

JAMA Dermatology