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We exclude overweight individuals

If side effects continue, switching to a different weekly injectable option may help

Antacids such as Tums can help short-term

GLP-1 is degraded in the bloodstream in less than a minute, whereas this peptide, consisting of 39 amino acids, exendin-4, could last for more than two hours

Further, GLP-1RAs block the adhesion of monocytes to endothelium induced by oxidized LDL via extracellular signal-regulated kinase (ERK) 5-Kruppel-like factor (KLF)2 signaling pathway to prevent endothelial permeability [107, 108]

Semaglutide works by binding to and activating the GLP-1 receptor, which is involved in glucose regulation and appetite control