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The investigators reported sustained increases in growth velocity over 8 years of mecasermin treatment, with a favorable safety profile in this pediatric population [2]

Declaration of Artificial Intelligence (AI): AI was not utilized in this submission

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Increases local concentration while reducing systemic exposure

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The protective effect of l-Carnitine on PFOS-impaired lysosomal function was observed through AO staining for lysosome membrane stability (Fig