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Thus, HIF-2-induced fatty acid synthesis using glutamine-derived citrate can be therapeutically targeted in several cancers, especially ccRCC

It is produced exclusively through solid-phase peptide synthesis and appears as a white lyophilized powder in its research-grade form

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In the case of mTOR signaling, the direct PA effector is the FRB domain of the mTOR kinase itself, though engagement of this protein by the azo-PA analog was not assessed

[11] PubChem NNMTi (5-Amino-1-methylquinolinium iodide compound listing).