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Experimental research has demonstrated that PCs therapy diminishes the proliferation and migration of human aortic smooth muscle cells (HASMCs) triggered by AGEs by elevating UCH-L1 protein levels, reducing IB- degradation, and curtailing NF-B nuclear translocation in a dose-responsive manner (Qian et al., 2011)
Pimenta F, Maroco J, Ramos C, Leal I
RT/CT, radiotherapy/chemotherapy
ADA Standards of Care 2025) recommend that patients with type 2 diabetes and atherosclerotic cardiovascular disease (ASCVD) (or high risk) should be on a GLP-1 RA with proven CV benefit (or an SGLT2 inhibitor) as part of their regimen, independent of A1c, because of the outcome benefits ( [9] ) ( [144] )
JanssenAWFHoubenTKatiraeiSDijkWBoutensLVan Der BoltNet al
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