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The phosphorylation state of MLC-2 therefore reflects a dynamic balance between MLCK-mediated phosphorylation and MLCP-mediated dephosphorylation, with increased phosphorylation generating ATP-dependent actomyosin contraction and elevated cytoskeletal tension at the apical junctional complex (Jin and Blikslager, 2020)

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Despite not placing mice on a histamine-free diet, our work defines a key role for endogenous MC-derived histamine in driving phenotypic severity

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Not all brands fortify equally, so its worth comparing labels to find those with higher B12 content