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doi: 10.1172/JCI113450 110 NorrelundHFrystykJJorgensenJOMollerNChristiansenJSOrskovHet al

Interferons and retinoic acid both upregulate DPP4 gene expression through the signaling pathway that involves the signal transducer and activator of transcription alpha (STAT1)

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GSH behaves as redox sensor at the DNA synthesis onset by maintaining nuclear architecture providing the appropriate redox environment for DNA replication and safeguarding DNA integrity (72) and is a key regulator of epigenetic events critical in cell proliferation regulation and cellular resistance to apoptosis (73)