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However, using variants that do not dimerize, it has been recently described that homodimer formation of GCL is not required for enzyme activation (Yang et al., 2019)

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At minimum, screening should include depression and suicidal ideation

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Rather than introducing external hormones, it encourages the body to resume endogenous production patterns

Most commonly, patients will present with a variety of generalized symptoms including, but not limited to, nausea/vomiting, dehydration, hypoglycemia, diarrhea and abdominal pain