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These data suggest that even though GH pulse parameters are reduced in the overweight and obese in association with excess VAT, stimulation with an exogenous GHRH analog (tesamorelin) for 2 wk can increase critical parameters of GH pulsatility and raise IGF-I to a clinically significant level in this group

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Shen M, Li Y, Wang Y, Shao J, Zhang F, Yin G, et al

Compare this to the substances on a standard drug panel, most of which are small organic molecules with molecular weights in the range of 200 to 400 daltons, and you begin to see why immunoassay cross-reactivity is essentially impossible under normal conditions