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10.1073/pnas.0505294102 Proc

Moreover, mice with systemic knockout of SLC25A39 (including the heart) exhibited severe anemia, a complete lack of red blood cells, and iron overload [62]

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This oxidative stress can lead to cellular damage if not adequately managed

USA 85:6237-6241

Dissolution is an extrinsic property affecting a wide range of chemical, physical and crystallographic factors including complexation, particle size, surface properties, and modifications to the solid-state or formulation strategies that improve solubility