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13 Studies investigating the status of claudins and other TJ-associated proteins in human biopsy specimen from chronic inflammatory conditions (Inflammatory Bowel Disease (IBD)) 14 have demonstrated differential changes in their total cellular content and/or distribution (see Table 1)

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Rituximab (Rituxan, Truxima) Rituximab (Rituxan) and biosimilar rituximab-abbs (Truxima) are biologic agents that deplete B cells (cells that produce antibodies) by binding to CD20+, a protein on the surface of certain B cells

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