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If there is food or too much water in the way, the semaglutide cannot pass through the lining and into the bloodstream

Contact your healthcare provider if you have symptoms, such as pain in your upper stomach (abdomen), fever, yellowing of the skin or eyes (jaundice), or clay-colored stools

Research shows that certain food ingredients will make your symptoms worse

GLP-1 Patches vs Injections: At a Glance What is a GLP-1 agonist medication

Avocado, olive oil, nuts, seeds, and fatty fish like salmon provide essential fatty acids without the heavy, greasy quality that triggers GI distress

Semaglutide's appetite-suppressing effects depend on the medication's dose and your body's GLP-1 sensitivity, not meal timing around injection