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This effect attenuates postprandial glucose excursions, though tachyphylaxis (reduced response over time) to this particular effect may occur with chronic GLP-1 receptor agonist therapy

Although compounds such as vitamins, polyphenols, and plant-derived molecules have demonstrated promise in preliminary studies, more comprehensive clinical trials are needed to confirm their therapeutic value, determine optimal dosages, and assess long-term safety

Correct imprinting should lead to expression of the paternal allele only and sufficient expression of IGF-II for normal growth

PMCID: PMC11090168

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