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Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1

Falck E, Karlsson S, Carlsson J, Helenius G, Karlsson M, Klinga-Levan K

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Women should avoid melanotan-2 at high doses due to unpredictable melanocyte stimulation

In a double-blind, randomized, controlled trial involving 101 patients who underwent major hepatectomy, the perioperative administration of pentoxifylline significantly increased the regenerative capacity of small remnant livers (remnant liver to body weight 1.2%)