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Computational tools such as antiSMASH [65], PREDetector [66] or PRISM [67] may be efficiently utilized to detect such BGCs, predict how they are regulated or foresee the structural core of the compound produced by those genes

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Disruptions to Core Clock Genes (Basic Science) Disruptions to core circadian clock proteins, specifically Bmal1 , has also resulted in increased reactive oxygen species, which is critical during mediation/exacerbation of damage during reperfusion in ischemia (Peek et al., 2017)