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Subsequent reports of dramatic weight loss in patients led Novo Nordisk, the Danish company that makes Ozempic, to repackage it

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This is the first oral GLP-1 medication approved by the FDA and is set to ignite a price war with other weight loss medication competitors

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Those KEAP1-binding competitors, such as p21 Cip1/WAF1 and BRCA1, were found interacting with NRF2 and thus block the association of KEAP1 with NRF2 [18, 19]

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