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Phase 2 subjects on 150mg/day averaged 13.8% weight loss with no muscle loss reported

Instead of decreasing, HFSCs originated from Sox9 + hair peg cells persisted and expanded after one round of hair cycle to become essentially all of the HFSCs in the bulge and most of the secondary hair germ cells below the bulge

[PubMed] [Google Scholar] Quimby JM, Gustafson DL, Samber BJ et al: Studies on the pharmacokinetics and pharmacodynamics of mirtazapine in healthy young cats, J Vet Pharmacol Ther (in press)

However, it may alter the stability or solubility of some medications

Increased oxidative stress and altered activities of erythrocyte free radical scavenging enzymes in autism

Crist BL, Alekel DL, Ritland LM, Hanson LN, Genschel U, Reddy MB: Association of oxidative stress, iron, and centralized fat mass in healthy postmenopausal women