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TABLE 4 Clinical studies elucidating the use of antidiabetics against ocular conditions other than glaucoma

Cuenoud B, Ipek , Shevlyakova M, Beaumont M, Cunnane SC, Gruetter R, et al

Bloodbrain barrier permeability is induced in AOM mice via a mechanism involving the TGF 1-driven SMAD3-dependent upregulation of MMP9 expression and decrease of claudin-5 expression

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Clean label: no high-concern chemicals listed

This finding aligns with prior research in which the levels of decanoic acid, octanoic acid, and 2- and 3-hydroxybutyric acids were increased in the sera and cerebral dialysate of patients with sTBI [34]