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A comprehensive analysis of the known effects of GLP-1 and GLP-1RAs on cognitive, cellular, and molecular changes in NDD in preclinical and clinical studies have shown that both natural GLP-1 and its analogues, GLP-1RAs (dulaglutide, exenatide, liraglutide, lixisenatide, semaglutide, and tirzepatide) improve cognitive and motor functions

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In 1965 Brown moved to Canada where he took up a faculty position in the Department of Physiology at the University of British Columbia

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Additionally, Mazdutide improves insulin sensitivity and helps reduce liver fat content, further aiding in blood sugar regulation

doi: 10.1093/ecco-jcc/jjy004 5 AdolphTEMeyerMSchwrzlerJMayrLGrabherrFTilgH