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Researchers may also use animal models that overexpress abnormal tau proteins or inject tau aggregates to study their role in the disease

This is decision point time

Miniard AC, Middleton LM, Budiman ME et al (2010) Nucleolin binds to a subset of selenoprotein mRNAs and regulates their expression

However, further dose-response analysis and adjustment for intake of other vitamin and mineral supplements indicated that all-cause mortality risk was significantly increased by 7% only at a dose of 2,000 IU/day, which is notably higher than the UL for adults (1,100 IU/day of synthetic tocopherol or 1,500 IU/day of natural tocopherol)

Lassmann, H., & van Horssen, J

Yeshitila et al., 2024