How to Maintain a Healthy Diet and Stay on Track Even the best-laid plans can be hard to stick to if you're feeling nauseated or full
A review of the new GLP-1 receptor agonist/basal insulin fixed-ratio combination products
Brand names include Ozempic, Wegovy, Mounjaro, and Zepbound
While the specific mechanism causing the effects on the gastrointestinal tract are not fully elucidated, studies suggest GLP-1 and its analogues likely exert effects on the vagus nerve and inhibit cholinergic neurotransmission in the gastrointestinal system to prevent movement of the intestine
In September 2025, Lilly quietly terminated one of its two Phase 2 trials for strategic business reasons. 9,10 Scholar Rock (Apitegromab): A selective myostatin inhibitor that only blocks latent myostatin activation, potentially offering a cleaner mechanism
Studies show that 40 to 85 percent of people taking standard doses of GLP-1s have side effects, most often gastrointestinal troubles like nausea and vomiting
