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It was synthesized mainly through genetic engineering and other biological methods, which involved technical difficulties and high production costs and was inconducive to large-scale production

Bjerre Knudsen L, Madsen LW, Andersen S, Almholt K, de Boer AS, Drucker DJ, Gotfredsen C, Egerod FL, Hegelund AC, Jacobsen H, Jacobsen SD, Moses AC, Mlck AM, Nielsen HS, Nowak J, Solberg H, Thi TD, Zdravkovic M, Moerch U

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For example, all children born in the United States are screened for phenylketonuria, a condition caused by an inability to break down the amino acid phenylalanine, a component of some artificial sweeteners

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Targeted deletion of Tcf7l2 in adipocytes promotes adipocyte hypertrophy and impaired glucose metabolism