If your engine is covered in grease and grime (solvents and heavy metals), its not as efficient and your cars performance suffers
For example, this study by Funk et al
Their role in cellular signaling and energy regulation makes them valuable tools for controlled laboratory testing
The peptides mechanism of action through beta-3 adrenergic receptors in adipose tissue is entirely separate from insulin signaling and glucose uptake pathways
But, if you stop the medicine, you might gain some or all of the weight back
Aquac Res 32:206215 Ding Z, Liu Y, Han J, Liu X, Zheng Y, Li W, Xu Y (2020) Dietary lipid supplementation could significantly affect the growth, fatty acid profiles, and expression of PPAR, leptin, and adiponectin genes in juvenile genetically improved farmed tilapia