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Studies have shown that although many cells express APEX2 at low levels, it exhibits improved thermal stability and higher biotinylation activity compared to APEX

Kotani T, Aratake Y, Hirai K, Fukazawa Y, Sato H, Ohtaki S

It is a famously hard target for small-molecule agonism

Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines

This excess bilirubin can weigh down the livers conjugation ability, resulting in the accumulation of unconjugated bilirubin in bile

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