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Characterization of hypothermic intestinal ischemia-reperfusion injury in dogs: effects of glycine

Animal studies demonstrate that IGF-1 treatment reduces circulating free fatty acid levels, potentially through increased muscle uptake and oxidation combined with reduced adipose tissue lipolysis

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10.1111/j.1525-139X.2012.01081.x 95

The IGF-1 receptor consists of two alpha subunits and two beta subunits linked by disulfide bonds, forming a heterotetrameric structure