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PMOS also tends to be associated with excess weight, although people at a healthy weight can also have the condition, says Marilyn Tan, MD, an endocrinologist at Stanford Medicine in California

Clinical Efficacy: Weight Loss Results and Timelines Semaglutide trials showed average weight reductions of 1022% from baseline over 68 weeks, depending on dose level and patient population

That doesn't mean they're not worth considering

In some cases, semaglutide usage has led to changes in blood sugar levels, which can also affect kidney function

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This tallied with anecdotal reports some clinicians have received