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[See Dosage and Administration (2.2), Contraindications (4), Warnings and Precautions (5.1) and Clinical Pharmacology (12.3).] Sitagliptin Sitagliptin is excreted by the kidney, and sitagliptin exposure is increased in patients with renal impairment

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Glial cells to a very great extent define neuropathology, its progression and outcome: as long as glial defence prevails, the pathological process is resolved, whereas the failure of glial defence results in neuronal death and neurological deficits