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Harnessing incretin hormones beyond GLP-1: novel incretin combinations There is increasing interest in other incretin hormones that may act on the kidney

To investigate the stimulation mechanism of GLP-1 secretion, we examined the response of intestinal GLUTag cells to glucose stimulation and Gs activation by deoxycholic acid (DCA) through G-protein coupled bile acid receptor 1 (GPBAR1) and L-glutamine, which are prevalent in daily ingested proteins

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have divulged glucagon-like peptide 1 receptor (GLP-1R) agonists reported to be useful for the treatment of type 1 diabetes, atherosclerosis, type 2 diabetes, obesity, nonalcoholic or metabolic dysfunction-associated steatohepatitis (NASH/MASH), hypertension, diabetic complications and coronary heart disease among others

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