The company said the investigational GIP, GLP-1 glucagon triple hormone receptor agonist may offer another option for both diabetes and obesity
Thus, BED appears to involve GLP-1 dysregulation without consistent endocrine abnormalities, implying that GLP-1 RA therapy works through supraphysiological receptor activation and modulation of central reward circuitry, rather than by correcting a hormonal deficit [55]
Researchers did a study that lasted nearly a year with 338 adults who were not diabetic but were overweight or obese
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To put that into perspective, Ozempic and Wegovy are GLP-1 receptor agonists, while Zepbound and Mounjaro are dual GIP/GLP-1 receptor agonists