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Many users were never warned of the risk of vision loss

Am J Kidney Dis 79(2):244256.e1

Our goal is not to sell more medications

These drugs are produced by Novo Nordisk and Eli Lilly, which both recently announced agreements with the Trump administration to lower prices

GLP-1RAs suppress NLRP3 inflammasome activation via attenuating the expression of NLRP3, apoptotic speck containing protein (ASC), and cleaves caspase 1 (p10) [111]

This asymmetric dual engagement is intended to expand the therapeutic window, mitigate GLP-1driven tolerability limits, enable higher effective chronic dosing, and translate into more durable weight loss with robust glycemic control versus pure GLP-1 agonists